This is my opinion on the domain and .US.
While I like .US for building websites, I think it's a great cheap alternative for the .com, where the .com is not available. For instance, Drugs.US would be a great pick considering the .COM is not available and the price of said domain would be much too high. However, in my opinion, non-keyword .US don't have inherent value in the name alone at this point in time. For instance, if you owned smiths drugs and you wanted a domain name representing your business, you'd be inclined to buy SmithsDrugs.US because smithsdrugs.com wouldn't be available and you don't want to change your business name. However, if you're only trying to build an online presence (as would be suggested with onlinedrugs.tld), If I were a buyer with no offline presence, I'd purchase something like 'closeoutdrugs.com' which is available, memorable enough, and a .com over a random .us domain.
Since I mostly develop domain names and I don't typically sell my domains, thats just my opinion from more of a buyers perspective.